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Review
Damage control articular surgery: Maintaining chondrocyte health and minimising iatrogenic injury.
- Thomas A Howard, Iain R Murray, Anish K Amin, A Hamish Simpson, and Andrew C Hall.
- Department of Trauma and Orthopaedics, Royal Infirmary of Edinburgh, 49 Little France Crescent, EH16 4SA, UK.
- Injury. 2020 May 1; 51 Suppl 2: S83-S89.
AbstractArticular cartilage has limited intrinsic regenerative potential. The maintenance of healthy articular cartilage is essential to prevent joint degeneration and the morbidity associated with arthritis. In this review, we outline the structure and function of healthy articular cartilage. We summarise some of the recent literature outlining the influence of surgical factors on chondrocyte health. These factors include mechanical injury from instrumentation and drilling, drying, and the influence of irrigation fluids, antimicrobial solutions and local anaesthetics. We demonstrate that there is scope for improving cartilage viability at the time of surgery if simple chondroprotective measures are routinely adopted.Crown Copyright © 2019. Published by Elsevier Ltd. All rights reserved.
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