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Randomized Controlled Trial Clinical Trial Controlled Clinical Trial
The antiemetic effect of dixyrazine in postoperative patients-- a double-blind study.
- I Kivalo and P Rosenberg.
- Ann Chir Gynaecol. 1976 Jan 1; 65 (4): 28n-9.
AbstractA double-blind controlled study based on 197 women undergoing legal abortion (part I) or gynaecological surgery (part II) was employed to estimate the antiemetic effect of dixyrazine. Dixyrazine or part I) or intramuscularly at the end of anaesthesia (part II) and repeated when necessary. The follow-up period lasted 12 and 18 hours, respectively. Overall, a marked antiemetic response in the dixyrazine groups was observed when compared with the placebo treated groups in both part I and II (p less than 0.001). Dixyrazine proved to be superior to placebo especially in patients who were not prone to nausea or who received no major postoperative analgesics (p less than 0.001).
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