• Wesley P Gilliam, Julia R Craner, Julie L Cunningham, Michele M Evans, Connie A Luedtke, Eleshia J Morrison, Jeannie A Sperry, and Larissa L Loukianova.
• Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, Minnesota. Electronic address: gilliam.wesley@mayo.edu.
• J Pain. 2018 Jun 1; 19 (6): 678-689.

AbstractChronic pain is a major public health concern, and widespread use of prescription opioids for chronic pain has contributed to the escalating problem of opioid use disorder. Interdisciplinary pain rehabilitation programs (IPRPs) can be highly effective in discontinuing opioids in patients with chronic pain while also improving functional status. This study sought to examine self-report and performance-based functional outcomes of 2 cohorts of patients enrolled in a 3-week IPRP: patients engaged in interdisciplinary pain treatment and physician-supervised opioid taper versus nonopioid users engaged in interdisciplinary treatment. Immediate and long-term treatment outcomes were assessed using a series of 2 (group: opioid use, no opioid use) × 2 (period: pretreatment, post-treatment) and 2 (group: opioid use, no opioid use) × 2 (period: pretreatment, 6 months post-treatment) mixed model analyses of variance. Group × Period interactions were nonsignificant whereas period effects were significant for all outcomes in directions indicating improvement (Ps < .001) at discharge from the program and at 6 months, irrespective of opioid use status. Results support the assertion that IPRPs lead to significant improvements in subjective as well as objective indices of function, irrespective of opioid use status. Implications for our findings are discussed.Copyright © 2018 The American Pain Society. Published by Elsevier Inc. All rights reserved.

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