• Fethi Gül, İsmet Sayan, Umut Sabri Kasapoğlu, Derya Özer Erol, Mustafa Kemal Arslantaş, Ismail Cinel, and Zuhal Aykaç.
• Department of Anesthesiology and Critical Care, Marmara University Pendik Training and Research Hospital, İstanbul-Turkey.
• Ulus Travma Acil Cer. 2019 Nov 1; 25 (6): 561-566.

BackgroundIntra-abdominal hypertension (IAH) is a frequent cause of acute kidney injury (AKI) among critically ill patients who have risk factors. This study aimed to determine the relation between Abdominal Perfusion Pressure (APP) and AKI showed by the Doppler-based renal resistive index (RRI).MethodsIn this study, 38 patients older than 18 years old who received mechanical ventilation and had risk factors for the development of IAH were prospectively studied. All measurements and parameters were divided into two groups according to renal dysfunction (Group I: RRI <0.72 vs Group II: RRI >0.72).ResultsThe mean IAPs were not significant between the groups, 11.5±6.9 mm Hg in Group I (n=35) and 13.5±5.8 in Group II (n=33), respectively. APPs were statistically higher in Group I (81.2±13.6) than Group II (66.4±9.5) (p<0.001). The AUC for the association between APP at RRI >0.72 was 0.802 (p<0.001), with the APP ≤72 mmHg having a sensitivity of the 76% (95% CI 58-89%) and a specificity of 71% (95% CI 54-85%).ConclusionOur findings suggest that an APP with a threshold of ≤72 mmHg is associated with a significant increase in renal RRI, which may be predictive of worsening of renal perfusion.

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