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- Rob Dallapiazza, M Sean McKisic, Binit Shah, and W Jeff Elias.
- Department of Neurosurgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
- Neurosurg. Clin. N. Am. 2014 Jan 1; 25 (1): 47-58.
AbstractSurgical neuromodulation has emerged as the primary method to treat the medically refractory symptoms of essential tremor and Parkinson disease. With reversible manipulation of CNS neurons, neuromodulation can be used to intraoperatively localize and verify a stereotactic target, and to chronically treat movement disorders. This article discusses the historical advances in stereotactic surgery using various modalities of neuromodulation leading to contemporary treatment. Electrical neuromodulation, or deep brain stimulation, is emphasized as the major surgical intervention with a discussion of the technique, surgical targets, and clinical outcomes. A comparison of neuromodulation techniques is presented. Copyright © 2014 Elsevier Inc. All rights reserved.
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