• World Neurosurg · Feb 2020

    Case Reports

    Cerebellar Arteriovenous Malformation with Coexistent Hemangioblastoma.

    • Jorge A Monserrate Marrero, Andrés E Monserrate Marrero, Juan L Pérez Berenguer, Eduardo Labat Álvarez, Juan M Corona, and Caleb Feliciano.
    • School of Medicine, University of Puerto Rico, Medical Science Campus, San Juan, Puerto Rico.
    • World Neurosurg. 2020 Feb 1; 134: 495-500.

    BackgroundThis is a case of a man aged 40 years with a past medical history of smoking, hypertension, polycythemia vera, intellectual disability, and schizophrenia who presented with generalized headaches, progressive loss of balance, and visual disturbance for 1 month.Case DescriptionHead computed tomography and magnetic resonance imaging revealed a right cerebellar hematoma associated to heterogenous lesion with cystic components and flow-voids in the right cerebellar hemisphere. A ventriculoperitoneal shunt was placed with partial improvement of symptoms. Further vascular studies confirmed presence of a vascular nidus with significant arteriovenous shunting. The patient later required intervention for cerebellar arteriovenous malformation (AVM) removal. Microscopic evaluation of the lesion showed the AVM nidus, as well as large, vacuolated stromal cells and numerous thin-walled vessels. Immunostaining with inhibin and S-100 highlighted the stromal cells with numerous lipid-containing vacuoles. The earlier mentioned findings were consistent with the diagnosis of an AVM with coexistent hemangioblastoma of the right cerebellar hemisphere.ConclusionsCoexistence of hemangioblastomas and AVMs are extremely rare, and only 3 cases have been reported previously in the literature.Copyright © 2019 Elsevier Inc. All rights reserved.

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