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Journal of critical care · Feb 2020
Multicenter StudyTHAI-ICU score as a simplified severity score for critically ill patients in a resource limited setting: Result from SEA-AKI study group.
- Theerapon Sukmark, Nuttha Lumlertgul, Kearkiat Praditpornsilpa, Kriang Tungsanga, Somchai Eiam-Ong, and Nattachai Srisawat.
- Thungsong Hospital, Nakhon Si Thammarat, Thailand.
- J Crit Care. 2020 Feb 1; 55: 56-63.
PurposeTo create a simplified ICU scoring system to predict mortality in critically ill patients that can be feasibly applied in resource limited setting with good performance of predicting hospital mortality.Materials And MethodsA retrospective study from prospective cohort was created consisting of adult patients who were admitted to an ICU of 17 centers across Thailand from 2013 to 2015. A development cohort (n = 3503) and a validation cohort (n = 1909) were randomly selected from the available enrollment data.ResultsIn the development cohort, the predictors of the simplified score 6 variable model were low Glasgow coma score (GCS), low mean arterial pressure or need vasopressor, positive net-fluid balance, tachypnea, thrombocytopenia, and high blood urea nitrogen. In the validation study of THAI-ICU, AUC (95%CI) was 0.81(0.78-0.83). At the optimum cutoff value of 9; the sensitivity, specificity, positive likelihood ratio were 72%, 73%, and 2.72 respectively. The Hosmer-Lemeshow - C statistic was 13.5 (p = .2) and the Brier score 95% CI was 0.16 (0.15, 0.17).ConclusionsThe THAI-ICU score is a new simplified severity score for predicting hospital mortality. The simplicity of the score will increase the possibility to apply in resource limited settings.Copyright © 2019. Published by Elsevier Inc.
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