• Korean J Ophthalmol · Sep 2005

    Review Case Reports

    Wernicke-Korsakoff syndrome associated with hyperemesis gravidarum.

    • Chang-Kyoon Yoon, Moo-Hwan Chang, and Dong-Cho Lee.
    • Department of Ophthalmology, Dankook University College of Medicine, Cheonan, Korea.
    • Korean J Ophthalmol. 2005 Sep 1; 19 (3): 239-42.

    PurposeThe authors hereby describe a case of Wernicke-Korsakoff syndrome with accompanying ocular findings that is caused by hyperernesis gravidarum.MethodsWe experienced a 27-year-old female at 12 weeks of pregnancy, who visited our clinic because of weight loss, gait disturbance, decreased mentality and dizziness after prolonged vomiting for 2 months. Neurological examination demonstrated ataxia of gait and loss of orientation. Ophthalmologic examination showed decreased visual acuity, upbeat nystagmus, diplopia and retinal hemorrhage.ResultsWe report a relatively rare case of Wernicke-Korsakoff syndrome with ophthalmic symptoms induced by hyperemesis gravidarum.ConclusionsIf a pregnant women has symptoms of severe vomiting along with other ocular findings such as retinal hemorrhage or restricted extraocular movement, one must suspect the diagnosis of Wernicke-Korsakoff syndrome, and should start appropriate treatment immediately.

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