• Med Klin · Apr 1996

    [Preoperative risk assessment of children with Duchenne muscular dystrophy and relevance for anesthesia and intra- and postoperative course].

    • K H Wollinsky, C Weiss, M Gelowicz-Maurer, P Geiger, H H Mehrkens, and T Naumann.
    • Abteilung Anästhesiologie/Intensivmedizin, Rehabilitationskrankenhaus, Orthopädische und Neurologische Klinik der Universität Ulm.
    • Med Klin. 1996 Apr 12; 91 Suppl 2: 34-7.

    BackgroundPatients suffering from muscle disorders have an elevated anesthetic risk, i.e. to develop malignant hyperthermia or rhabdomyolysis. In addition serious cardial and pulmonal complications are imminent during anesthesia for surgery.Patients And MethodsWe investigated retrospectively the preoperative risk factors of 81 Duchenne patients undergoing 101 anesthesia (79 for muscle releasement operations and 23 for spine surgery) and the relation to possible complications due to the anesthesia and the intra- and postoperative course.Results And Discussion83% of the patients showed pathologic ECG, 26% cardiac insufficiency in echocardiography, 31% pathologic X-rays of the thorax and 73% serious pulmonary restriction. Consequently avoiding of anesthetic agents with a high trigger potential for developing malignant hyperthermia (i.e. halothane or muscle relaxants type succinylcholine) prevented severest complications as malignant hyperthermia, rhabdomyolysis or cardiac arrest. Nevertheless other complications (i.e. arrhythmia, cardiac insufficiency) occurred due to the cardiac and pulmonary limitations more pronounced in the older patients of the spine surgery group.

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