• Anaesth Intensive Care · Dec 2000

    Case Reports

    Intraoperative high-dose remifentanil in a patient on naltrexone therapy.

    • C A Schwab and D A Wright.
    • Department of Anaesthesia, Royal Perth Hospital, Perth, Western Australia.
    • Anaesth Intensive Care. 2000 Dec 1; 28 (6): 701-3.

    AbstractNaltrexone hydrochloride is a synthetic opioid receptor antagonist recently used in efforts to provide rapid opioid detoxification. Other clinical uses include alleviating itch due to cholestasis or uraemia. We report a case where unrecognised naltrexone therapy for itch affected anaesthesia, resulting in high opioid requirements. We also discuss other analgesic options utilized.

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