• Sharven Taghavi, Lynn M Wilson, Stacey H Brann, John Gaughan, and Abeel A Mangi.
• Department of Surgery, Temple University Hospital, Philadelphia, Pennsylvania, USA.
• J. Card. Fail. 2012 Sep 1; 18 (9): 688-93.

BackgroundUnited Network for Organ Sharing adult heart transplant criteria recommend against using same-sex donors with a donor-recipient body weight ratio <0.7. The same criteria recommend against a female donor to male recipient body weight ratio <0.9. We attempted to determine if transplantation with low donor-recipient body weight ratios can be safely performed.Methods And ResultsTransplants with same-sex donor-recipient body weight ratio <0.7 and female donor-male recipient body weight ratio <0.9 were compared with age- and sex-matched control subjects with ideally matched donor weights. Of the 123 patients undergoing transplantation, 23 met low donor-recipient body weight ratio criteria. This cohort was compared with 22 ideally weight-matched patients. There was no difference in survival at 1, 5, and 10 years (P = .68). Freedom from rejection (52.2 vs 50.0%; P = 1.0), creatinine clearance change (-1.3 vs 5.7 mL/min; P = .88), duration of inotropic support (191.5 vs 208.8 h; P = .65), and duration of mechanical ventilation (156.3 vs 84.5 h; P = .52) were similar. Intensive care (290.5 vs 368.6 h; P = .71) and hospital length of stay (35.4 vs 36.7 d; P = .94) were not different.ConclusionsAccepted donor-recipient weight match criteria may be extended to increase the donor pool.Copyright © 2012 Elsevier Inc. All rights reserved.

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