• Menno Sluzewski and Willem Jan van Rooij.
• Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, the Netherlands.
• AJNR Am J Neuroradiol. 2005 Aug 1; 26 (7): 1739-43.

Background And PurposeThe purpose of this study was to assess the incidence of early rebleeding after coiling of a ruptured cerebral aneurysm, assess the clinical outcome, and identify risk factors for this event.MethodsEarly rebleedings occurred in 6/431 (1.4%) consecutive patients after coiling of a ruptured aneurysm. Clinical condition at the time of treatment, aneurysm location and size, initial aneurysm occlusion, timing of coiling, and the presence of an adjacent intracerebral hematoma in the six patients with early rebleedings were compared with the remaining 425 patients.ResultsIncidence of early rebleeding after coiling of a ruptured aneurysm was 1.4%, and mortality was 100%. Independent risk factors are the presence of an adjacent intracerebral hematoma and small aneurysm size. Dependent risk factors are location on the anterior communicating artery, initial incomplete aneurysm occlusion, and poor clinical condition at the time of treatment.ConclusionEarly rebleeding after coiling of ruptured aneurysms is a major concern, in particular because the mortality is very high. A more restricted postembolization anticoagulation strategy in high-risk aneurysms may possibly prevent the occurrence of this devastating event.

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