• A&A practice · Nov 2019

    Case Reports

    Undiagnosed Systemic Mastocytosis Presenting as Postoperative Distributive Shock: A Case Report.

    • Juan G Ripoll, Matthew J Ritter, Thomas B Comfere, Mark M Smith, Hartzell V Schaff, George D Gilkey, and Matthew A Warner.
    • From the Department of Anesthesiology and Perioperative Medicine.
    • A A Pract. 2019 Nov 15; 13 (10): 392-395.

    AbstractSystemic mastocytosis (SM) is a rare clinical condition resulting from a clonal proliferation of abnormal mast cells. The clinical presentation may vary from mild cutaneous manifestations to aggressive systemic symptoms including intermittent episodes of anaphylaxis. We present a case of a 69-year-old male with abrupt and recurrent episodes of anaphylaxis with refractory distributive shock following cardiac surgery with cardiopulmonary bypass. Following a complex postoperative course, a bone marrow biopsy ultimately confirmed the diagnosis. Although rare, SM should be considered in the differential diagnosis of postoperative patients with unexplained and recurrent episodes of distributive shock.

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