• Nicolas Dea, Anne L Versteeg, Arjun Sahgal, Jorrit-Jan Verlaan, Raphaële Charest-Morin, Laurence D Rhines, Daniel M Sciubba, James M Schuster, Michael H Weber, Aron Lazary, Michael G Fehlings, Michelle J Clarke, Paul M Arnold, Stefano Boriani, Chetan Bettegowda, Ilya Laufer, Ziya L Gokaslan, and Charles G Fisher.
• Division of Spine Surgery, Department of Orthopaedics, Vancouver General Hospital, University of British Columbia, Vancouver, Canada.
• Neurosurgery. 2020 Aug 1; 87 (2): 303-311.

BackgroundDespite our inability to accurately predict survival in many cancer patients, a life expectancy of at least 3 mo is historically necessary to be considered for surgical treatment of spinal metastases.ObjectiveTo compare health-related quality of life (HRQOL) in patients surviving <3 mo after surgical treatment to patients surviving >3 mo to assess the validity of this inclusion criteria.MethodsPatients who underwent surgery for spinal metastases between August 2013 and May 2017 were retrospectively identified from an international cohort study. HRQOL was evaluated using generic and disease-specific outcome tools at baseline and at 6 and 12 wk postsurgery. The primary outcome was the HRQOL at 6 wk post-treatment measured by the Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ).ResultsA total of 253 patients were included: 40 patients died within the first 3 mo after surgery and 213 patients survived more than 3 mo. Patients surviving <3 mo after surgery presented with lower baseline performance status. Adjusted analyses for baseline performance status did not reveal a significant difference in HRQOL between both groups at 6 wk post-treatment. No significant difference in patient satisfaction at 6 wk with regard to their treatment could be detected between both groups.ConclusionWhen controlled for baseline performance status, quality of life 6 wk after surgery for spinal metastasis is independent of survival. To optimize improvement in HRQOL for this patient population, baseline performance status should take priority over expected survival in the surgical decision-making process.© Congress of Neurological Surgeons 2019.

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