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Anasthesiol Intensivmed Notfallmed Schmerzther · Oct 2019
Case Reports[Severe Shock Symptoms Due to Ticagrelor Related Anaphylactoid Reaction Following ST Elevation Myocardial Infarction].
- Gregor A Schittek, Holger Simonis, Matthias Fischer, and Jens Soukup.
- Anasthesiol Intensivmed Notfallmed Schmerzther. 2019 Oct 1; 54 (10): 630-634.
BackgroundTicagrelor as a P2Y12 receptor antagonist is recommended in patients with acute coronary syndrome without a primary cardiosurgical therapy. Severe relevant side effects, especially anaphylactic reactions, have not yet been described in the current literature.Case PresentationWe describe the first documented case in the current literature with a severe anaphylaxis after ticagrelor in a 76-year-old male patient with ST-elevation myocardial infarction. The diagnosis seems to be objectivated by the observed time-related life-threatening event after repetitive administration of ticagrelor and the rapid stabilization after adequate anaphylactic treatment.ConclusionThis case should raise the awareness that a supposedly safe drug can still cause an anaphylactic shock.Georg Thieme Verlag KG Stuttgart · New York.
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