• Critical care clinics · Jan 2020

    Review

    The Future of Biomarkers.

    • Jean-Louis Vincent, Elisa Bogossian, and Marco Menozzi.
    • Department of Intensive Care, Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, Brussels 1070, Belgium. Electronic address: jlvincent@intensive.org.
    • Crit Care Clin. 2020 Jan 1; 36 (1): 177-187.

    AbstractNumerous compounds have been tested as potential biomarkers for multiple possible applications within intensive care medicine but none is or will ever be sufficiently specific or sensitive for the heterogeneous syndromes of critical illness. New technology and access to huge patient databases are providing new biomarker options and the focus is shifting to combinations of several or multiple biomarkers rather than the single markers that research has concentrated on in the past. Biomarkers will increasingly be used as part of routine clinical practice in the future, complementing clinical examination and physician expertise to provide accurate disease diagnosis, prediction of complications, personalized treatment guidance, and prognosis.Copyright © 2019 Elsevier Inc. All rights reserved.

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