• World Neurosurg · Feb 2020

    Review

    Tumours of the Neurohypophysis - One unit's experience and literature review.

    • Anouk Borg, Zane Jaunmuktane, and Neil Dorward.
    • Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. Electronic address: anoukmt@yahoo.com.
    • World Neurosurg. 2020 Feb 1; 134: e968-e978.

    ObjectiveTo evaluate and understand the clinical behavior and radiologic correlates of tumors originating from the posterior pituitary gland. To review the management strategy for these rare tumors and add to the limited existing literature.MethodsRetrospective review of 8 cases (5 pituicytomas, 2 spindle cell oncocytomas, and 1 granular cell tumor) managed at our institution between 2004 and 2019. The patients' clinical course, histologic features, and radiologic findings were reviewed. Their management and long-term follow-up is presented and compared with the literature.ResultsLong-term follow-up ranged from 1 to 9 years. There was 1 recurrence in a patient with spindle cell oncocytoma, and this was treated with radiotherapy. The endoscopically managed cases resulted in complete tumor excision with no recurrence.ConclusionsEpidemiologic data on primary tumors of the neurohypophysis is limited because of the rarity of these tumors. This study adds to the literature that these tumors behave as World Health Organization grade I tumors, although close follow-up is recommended as a few cases have shown recurrence. The endoscopic approach resulted in better gross total tumor resection rate in this series.Crown Copyright © 2019. Published by Elsevier Inc. All rights reserved.

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