• Shan-Han Yang, Chun-Yu Wu, Wen-Hsuan Tseng, Wen-Ying Cherng, Tzu-Yu Hsiao, Ya-Jung Cheng, and Kuang-Cheng Chan.
• Department of Anesthesiology, National Taiwan University, College of Medicine and Hospital, No. 7, Chung-Shan S. Rd., Taipei, Taiwan.
• J Formos Med Assoc. 2019 Jul 1; 118 (7): 1138-1143.

BackgroundNonintubation anaesthesia for laryngomicrosurgery (LMS) provides both excellent visualization of the surgical field and complete examination on vocal cord. However, adequate oxygenation remains challenging during nonintubated LMS. Recently, transnasal humidified rapid-insufflation ventilator exchange (THRIVE) has been reported effectively maintaining apneic oxygenation in patient with difficult airways. The feasibility and safety of nonintubated LMS with THRIVE was evaluated in this case series.MethodsFrom September 2016 to February 2017, a total of 23 patients receiving nonintubated LMS were included. Anaesthesia was induced and maintained through target-controlled propofol infusion and muscle relaxation with THRIVE oxygen support. Perioperative data were collected from medical records and analysed.ResultsThe mean (±SD) duration of the operation was 12.4 (±4.4) min. The mean (±SD) total anaesthesia time (from induction to emergence) was 24.1 (±6.4) min. 22 patients received nonintubated LMS with surgical satisfaction without intraoperative desaturation. One patient who underwent laryngeal tumour biopsy experienced a single episode of desaturation. A 5.5-mm tracheal tube was needed for short-term mechanical ventilation to regain SpO2 to 100%. No significant complication was noted in all patients. All patients discharged as per schedule on the next day after surgery as intubated LMS patients in our hospital.ConclusionNonintubated LMS with THRIVE is a feasible and safe alternative to intubated LMS with a small size tracheal tube to provide a better surgical field. However, for patients with easy-bleeding tumor, intubated LMS remains suggestive for better airway protection.Copyright © 2018 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.

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