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Best Pract Res Clin Anaesthesiol · Sep 2019
ReviewPain measurement and critical review of analgesic trials: pain scores, functional pain measurements, limits and bias of clinical trials.
- Adrien Lemoine, Valeria Martinez, and Francis Bonnet.
- Hôpitaux de Paris, Sorbonne Université, Faculté de Médecine Paris VI, Service d'Anesthésie-Réanimation Médecine Périopératoire, Hôpital Tenon, 4 rue de la Chine, 75020, Paris cedex, France.
- Best Pract Res Clin Anaesthesiol. 2019 Sep 1; 33 (3): 287-292.
AbstractRandomized clinical trials designed to assess analgesic agents and/or techniques used for postoperative pain control have several limitations, which are addressed in this article. Efficacy of analgesics cannot be limited to the evaluation of pain intensity or the amount of opioid rescue medication, but it also means to evaluate parameters such as the delay and duration of the effect, the number of patients with satisfactory pain control, and side effects. Because combination of analgesics is the standard of care in clinical practice, its value also needs to be documented. Eventually, analgesic treatments have to be considered in the settings of postoperative supportive care and enhanced recovery programmes after surgery.Copyright © 2019. Published by Elsevier Ltd.
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