• Anthony M Tonsbeek, Justus L Groen, and Vleggeert-Lankamp Carmen L A M CLAM Department of Neurosurgery, Leiden University Medical Centre, Leiden, The Netherlands..
• Department of Neurosurgery, Leiden University Medical Centre, Leiden, The Netherlands. Electronic address: m.tonsbeek@lumc.nl.
• World Neurosurg. 2020 Mar 1; 135: 28-34.

BackgroundAberrant vertebral artery loops are a rare clinical condition, with sparse data regarding the optimal treatment guidelines for individual patients. The heterogeneity of treatment options in the literature creates a problem when tailoring treatments to individual patients. In this review of the literature, multiple surgical treatments for cervical vertebral artery loops were analyzed and compared. In addition, this article provides a clinical case of a patient with a vertebral artery loop.MethodsA literature review was conducted to identify studies investigating surgical treatments for a vertebral artery loop. Different surgical techniques were examined and the involved techniques and approaches described. The outcomes were assessed for each study and the effectiveness of the treatment determined.ResultsTwelve articles met the inclusion criteria for this review. Six types of surgical interventions were found in the literature. Each intervention had similar postoperative results, leading to either a significant improvement or a complete resolution of symptoms.ConclusionsMultiple successful surgical interventions have been described in the medical literature. However, because of the lack of evidence-based studies, no surgical intervention protocol could be determined. Treatment should therefore be tailored to individual patients' characteristics. Because not every radiologically detected vertebral artery loop is the main reason for a patient's symptoms, a thorough multidisciplinary approach is justified and advocated in patients with an atypical presentation, before a neurosurgical intervention takes place. More deliberate clinical decisions can be made once the understanding of the pathogenesis of this rare disease entity has been established and treatment protocols formulated.Copyright © 2019 Elsevier Inc. All rights reserved.

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