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Stereotact Funct Neurosurg · Jan 2013
Long-term efficacy of stereotactic bilateral anterior cingulotomy and bilateral anterior capsulotomy as a treatment for refractory obsessive-compulsive disorder.
- Q J Zhang, W H Wang, and X P Wei.
- Department of Neurosurgery, The Affiliated Southeast Hospital of Xiamen University, Zhangzhou, China.
- Stereotact Funct Neurosurg. 2013 Jan 1; 91 (4): 258-61.
ObjectiveTo investigate the long-term efficacy and adverse effects of stereotactic bilateral anterior cingulotomy (BACI) and bilateral anterior capsulotomy (BACA) as a treatment for refractory obsessive-compulsive disorder (OCD) patients.MethodsSeven patients suffering from refractory OCD underwent stereotactic surgery and were followed for 12 months. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was used to assess the efficacy. The test was taken before and 6 and 12 months after surgery.ResultsThe mean Y-BOCS scores decreased significantly from 32.9 ± 4.7 at baseline to 20.6 ± 5.3 after 12 months. Five out of the 7 patients showed a decrease of more than 35%. During the 12-month follow-up, the effective rate had increased from 28.6 to 71.4%. There were no significant adverse effects observed after surgery.ConclusionsThe BACI and BACA were effective for the treatment of refractory OCD, and no significant adverse effects on long-term follow-up were found.Copyright © 2013 S. Karger AG, Basel.
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