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- Marci B Pepper, Catherine Njathi-Ori, and Michelle Ochs Kinney.
- Mayo Clinic Department of Anesthesiology and Perioperative Medicine, 200 First Street SW, Rochester, MN, 55905, USA. Pepper.Marci@mayo.edu.
- BMC Anesthesiol. 2019 Dec 14; 19 (1): 226.
BackgroundWe aim to describe the evaluation and management of a patient with the uncommon combination of both mitochondrial myopathy and possible malignant hyperthermia susceptibility as an important source of information and as a valuable example of the role of regional anesthesia for patients with these diagnoses.Case PresentationA 24 year old woman with a history of possible mitochondrial myopathy and possible malignant hyperthermia susceptibility presented for gynecologic surgery. Surgery was well tolerated with combined spinal epidural anesthesia as well as sedation with midazolam, ketamine, and fentanyl.ConclusionsAnesthetic management of patients with mitochondrial myopathy is challenging, made even more so with concurrent malignant hyperthermia susceptibility. This case adds an example to the literature of employing regional anesthesia as a safe approach to this complex care.
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