• Burns · Jun 2020

    Observational Study

    Resuscitation with albumin using BET formula keeps at bay fluid administration in burned patients. An observational study.

    • Pablo Blanco-Schweizer, Jesús Sánchez-Ballesteros, Beatriz Bendito, Ana I Martín, Lorena Fernández, Jose M Piqueras, Pedro Enríquez, and Jesús Blanco.
    • Intensive Care Unit, Hospital Universitario Rio Hortega, C/Dulzaina 2, 47012 Valladolid, Spain; Critical Care Burn Unit, Hospital Universitario Rio Hortega, C/Dulzaina 2, 47012 Valladolid, Spain. Electronic address: pblancosc@saludcastillayleon.es.
    • Burns. 2020 Jun 1; 46 (4): 860-867.

    AbstractBET (Biological Engineering Technology) formula uses fluids with high albumin concentration to resuscitate burn patients. It estimates fluid resuscitation as a function of Body Burned Surface Area (BBSA) (ml/h = BBSA (m2) × 220) and administers it through a combination of lactated ringer and 20% Albumin starting at a 1:1 relationship. The proportion of albumin is decreased every 8 h, and infusion rate is modified according to urinary output. The study's purpose was to review resuscitation related variables of all burned patients treated in our unit using BET formula. We retrospectively analyzed all patients admitted to our critical care burn unit during a five year period. Only those admitted within the first 12 h post-burn injury were considered. 40 patients met all inclusion criteria. Resuscitation volume during the first 24 h was 2.58 ml/kg/%BBSA, significantly less than Parkland's estimation (4 ml/kg/%BBSA; P < 0.05). Patients were successfully resuscitated showing a significant base excess increase and lactate clearance during the resuscitation period (base excess 120%; lactate 29%; P < 0.05). Burn related complications where: ARDS 27%, renal dysfunction 53%, wound deepening 20%, abdominal compartment syndrome 4.5%. In conclusion, BET formula is capable of resuscitating burn patients successfully, limiting fluid administration.Copyright © 2019 Elsevier Ltd and ISBI. All rights reserved.

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