• S Koch, A M Stegherr, R Mörgeli, S Kramer, E Toubekis, G Lichtner, F von Dincklage, and C Spies.
• Department of Anaesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany. Electronic address: susanne.koch@charite.de.
• Clin Neurophysiol. 2017 Oct 1; 128 (10): 2014-2021.

ObjectiveAnaesthesia-induced dynamics in EEG are dependent on age and level of anaesthesia, but distinct characterisation in children is incomplete. Here we analyse EEG dynamics in children related to age and level of anaesthesia.MethodsFrontal EEG recordings were obtained from 93 children (0-19years) during routine clinical anaesthesia. EEG segments were selected at four different levels of anaesthesia: emergence, light anaesthesia, deep anaesthesia, and very deep anaesthesia.ResultsTotal power differed significantly over age at deep (R2=0.314; p<0.0001) and very deep anaesthesia (R2=0.403; p<0.0001). Relative beta band power at light anaesthesia increased linearly with age (R2=0.239; p<0.0001). Level of anaesthesia caused significant differences for relative delta band power (increasing with anaesthetic depth), for relative beta band power and for spectral edge frequency (decreasing with anaesthetic depth) for all children (p<0.0001).ConclusionsEEG parameterin children were primary dependent on anaesthetic depth, where beta band power, delta band power and spectral edge frequency showed a linear relation. Age-dependency during anaesthesia procedure were only seen for single EEG parameters.SignificanceDifferent levels of anaesthesia can be identified by relative beta band power, relative delta band power and spectral edge frequency irrespective of the children's age.Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

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