• Behrad Ziapour, Elmira Mostafidi, Homayoun Sadeghi-Bazargani, Ali Kabir, and Ikenna Okereke.
• Tufts Medical Center, 800 Washington Street #1035, Boston, MA, 02111, USA. behradzpr@gmail.com.
• Eur J Trauma Emerg Surg. 2020 Apr 1; 46 (2): 337-346.

PurposeIn this systematic review, we analyzed the optimal time range to evacuate traumatic-retained hemothorax using video-assisted thoracoscopic surgery (VATS).MethodsWe searched PubMed, EMBASE, the Cochrane Register of Controlled Trials, Google Scholar, and the U.S. National Library of Medicine clinical trials database up to February 2019. Randomized controlled trials (RCTs) and observational studies with relevant data were included. Data were extracted from studies that reported the success, mortality, or length of hospital stay (LOS) after using VATS during at least two out of three of our time-ranges of interest: days 1-3 (group A), days 4-6 (group B), and day 7 or later (group C).ResultsSix cohort studies with 476 total participants were included in the meta-analysis. The patients in group A had a significantly higher success rate than those in group C (RR = 0.42; 95% CI = 0.21-0.84, p = 0.01). The total LOS for patients whose retained hemothorax was evacuated in group A was 4.7 days shorter than that for those in group B (95% CI =  - 5.6 to  - 3.8, p = 0.006). Likewise, group B patients were discharged 18.1 days earlier than group C patients (95% CI =  - 22.3 to  - 14, p < 0.001). Short-term mortality was not decreased by early VATS.ConclusionsOur results indicate that VATS should be considered within the first three days of admission if this intervention is the clinician's choice to evacuate a traumatic-retained hemothorax. Protocol registration number in PROSPERO: CRD42017046856.

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