• Arch. Pathol. Lab. Med. · Mar 2016

    Review Comparative Study

    Update on Pulmonary Fibrosis: Not All Fibrosis Is Created Equally.

    • Maxwell L Smith.
    • From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona.
    • Arch. Pathol. Lab. Med. 2016 Mar 1; 140 (3): 221-9.

    ContextThree distinct patterns of pulmonary fibrosis, including usual interstitial pneumonia, fibrotic nonspecific interstitial pneumonia, and airway-centered fibrosis, can be identified on surgical lung biopsies.ObjectivesTo compare the pathologic definitions, clinical and radiographic presentations, etiologies and differential diagnoses, treatments, and prognoses of usual interstitial pneumonia, fibrotic nonspecific interstitial pneumonia, and airway-centered fibrosis patterns, and to address the challenges and controversies related to pulmonary fibrosis.Data SourcesData were derived from published literature and clinical experience.ConclusionsAlthough there may be overlap, identification of the dominant form of fibrosis in a particular case can provide a general category of disease and assist in identifying an etiology.

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