• A&A practice · Jan 2020

    Case Reports

    Eighteenth Century Complications With 21st Century General Anesthesia: A Case Report of Scurvy.

    • Jeffrey R Zavaleta and Napoleon Burt.
    • From the Department of Anesthesia, Cook Children's Medical Center, Fort Worth, Texas.
    • A A Pract. 2020 Jan 1; 14 (1): 15-17.

    AbstractAutism spectrum disorder (ASD) may be associated with self-imposed dietary restrictions causing nutritional deficiencies, and the anesthesiologist must be aware of their potential clinical implications. Because humans are unable to produce ascorbic acid through endogenous metabolic pathways and children with ASD may avoid vitamin C-containing foods, vitamin C deficiency, or scurvy, may develop in patients scheduled for general anesthesia. Vitamin C deficiency may cause dysfunction in autonomic nervous system processes or pulmonary hypertension resulting in unexpected hemodynamic lability. We describe a child with ASD and limited dietary options leading to undiagnosed scurvy and intraoperative hypotension.

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