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Expert Rev Respir Med · Jan 2016
ReviewInhaled beclometasone dipropionate/formoterol fumarate extrafine fixed combination for the treatment of asthma.
- Ernesto Crisafulli, Andrea Zanini, Giovanna Pisi, Patrizia Pignatti, Gianluigi Poli, Mario Scuri, and Alfredo Chetta.
- a Department of Clinical and Experimental Medicine, Respiratory Disease and Lung Function Unit , University of Parma , Parma , Italy.
- Expert Rev Respir Med. 2016 Jan 1; 10 (5): 481-90.
AbstractInhaled therapy is often considered the cornerstone of asthma management and international guidelines recommend combination therapy of inhaled corticosteroids (ICS) and long-acting-beta2-agonists (LABA) in a large proportion of asthmatic patients. The effectiveness of ICS/LABA is dependent on the correct choice of device and proper inhalation technique, this influences drug delivery and distribution along the bronchial tree, including the most peripheral airways. The fixed combination of beclometasone dipropionate/formoterol fumarate (BDP/FF) is the only extrafine formulation available in pressurized metered dose inhaler (pMDI) and in dry powder inhaler (DPI). Here, we focus on the recent significant advances regarding BDP/FF fixed combination for the treatment of asthma.
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