• World Neurosurg · Mar 2020

    Case Reports

    Diffuse Leptomeningeal Glioneuronal Tumor: A unique leptomeningeal tumor entity.

    • Sarbesh Tiwari, Taruna Yadav, Jaya Pamnani, John M Mathew, Poonam Elhence, Kokkula Praneeth, Deepak Vedant, Pushpinder Singh Khera, Pawan Garg, and Varuna Vyas.
    • Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India.
    • World Neurosurg. 2020 Mar 1; 135: 297-300.

    BackgroundDiffuse leptomeningeal glioneuronal tumor (DLGNT) is a recent addition to the World Health Organization classification schema of brain tumors, under the heading of neuronal and mixed neuronal-glial tumors. DLGNTs have a classic imaging appearance. However, it has often been misdiagnosed owing to its rarity, its resemblance to granulomatous/leptomeningeal etiologies, and the clinical presentation.Case DescriptionWe have described the case of a 3-year-old girl who had presented with complaints of nonprojectile vomiting and altered sensorium that had been initially diagnosed and treated as a case of tubercular meningitis at a peripheral health facility. However, the nonresponse to antitubercular medication necessitated a repeat magnetic resonance imaging evaluation at our institute, which had revealed the classic imaging appearance of DLGNT. The diagnosis was further established by meningeal biopsy and the histopathological evaluation findings.ConclusionWe have described the classic imaging appearance of this rare brain tumor. Radiologists and clinicians should be aware of this entity to avoid misdiagnosis and a delay in management.Copyright © 2019 Elsevier Inc. All rights reserved.

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