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Neuroscience letters · Jul 1994
Comparative StudyNeurons dissociated from neocortex fire with 'burst' and 'regular' trains of spikes.
- E Guatteo, A Bacci, S Franceschetti, G Avanzini, and E Wanke.
- Istituto Neurologico C. Besta, Milano, Italy.
- Neurosci. Lett. 1994 Jul 4; 175 (1-2): 117-20.
AbstractNeurons acutely dissociated from neocortex slices of 14-16-day-old rats were patch-clamped in physiological conditions. Different pyramidal cells, spontaneously or in response to current steps, generate regular spiking and intrinsically bursting behaviour during long periods of time. We show that typical firing properties recorded in somatosensory neocortex slices are preserved in dissociated pyramidal neurons originating from the slices themselves, thus, providing a way for the related characterization of biophysical properties of currents in identified subtypes of pyramidal neurons.
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