• Semin Respir Crit Care Med · Aug 2007

    Review

    Pulmonary manifestations of systemic lupus erythematosus.

    • Beatrice Memet and Ellen M Ginzler.
    • Division of Rheumatology, State University of New York-Downstate Medical Center, Brooklyn, New York 11203, USA.
    • Semin Respir Crit Care Med. 2007 Aug 1; 28 (4): 441-50.

    AbstractSystemic lupus erythematosus (SLE) can affect the lung in multiple ways. All components of the respiratory system, including the pleura, pulmonary parenchyma, airways, vessels, and respiratory muscles can be involved in various degrees at some time in the disease course and contribute to its morbidity and mortality. This article reviews the clinical symptoms, imaging techniques, histopathology, prognosis, and treatment of pulmonary manifestations of SLE and the related disorder mixed connective tissue disease (MCTD), from a historical perspective and with regard to new insights into pathogenesis and therapy.

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