• Vu Q C Nguyen, William C Bock, Christine C Groves, Marybeth Whitney, Maria E Bennett, Tina E Lechman, Robert Strother, Julie H Grill, Kathryn W Stager, and John Chae.
• From the Department of Physical Medicine and Rehabilitation (VQCN, CCG, MW) and Department of Cardiology (WCB), Carolinas Medical Center, Charlotte, North Carolina; SPR Therapeutics, LLC, Cleveland, Ohio (MEB, TEL, KWS); NDI Medical, LLC, Cleveland, Ohio (RS, JHG); Department of Physical Medicine and Rehabilitation, Department of Biomedical Engineering, and the Cleveland Functional Electrical Stimulation Center, Case Western Reserve University, Cleveland, Ohio (JC); and Department of Physical Medicine and Rehabilitation, MetroHealth Rehabilitation Institute of Ohio, Cleveland, Ohio (JC).
• Am J Phys Med Rehabil. 2015 Feb 1; 94 (2): 146-53.

AbstractThis case report describes the first participant treated with a fully implantable, single-lead peripheral nerve stimulation system for refractory hemiplegic shoulder pain. During the 6-wk trial stage, a temporary lead was placed percutaneously near the terminal branches of the axillary nerve to the deltoid. The primary outcome measure was the Brief Pain Inventory-Short Form Question 3, a 0-10 pain numeric rating scale. The participant experienced 75% pain reduction and proceeded to the implantation stage, where he received a single-lead, implantable pulse generator. After 3 wks, the participant became pain-free. However, 7 wks after implantation, the system was turned off because of an unrelated acute medical illness. Hemiplegic shoulder pain reemerged with a Brief Pain Inventory-Short Form Question 3 score of 9. After 11 wks of recovery, peripheral nerve stimulation was reinitiated and the participant became pain-free through the 9-mo follow-up. At 12 mos, Brief Pain Inventory-Short Form Question 3 score was 1. This case report demonstrates the feasibility of a single-lead, fully implantable peripheral nerve stimulation system for refractory hemiplegic shoulder pain.

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