• Anesthesia and analgesia · Mar 2005

    Case Reports

    Transdermal buprenorphine for treating nociceptive and neuropathic pain: four case studies.

    • Rudolf Likar and Reinhard Sittl.
    • Pain Clinic, General Hospital Klagenfurt, St. Veither Strasse 47, 9026 Klagenfurt, Austria. r.likar@aon.at
    • Anesth. Analg. 2005 Mar 1; 100 (3): 781-5, table of contents.

    AbstractThe use of opioids for treating neuropathic pain is controversial, and some studies have indicated that neuropathic pain may be relatively insensitive to typical mu-opioid analgesics such as morphine. However, it is becoming clear that different opioids produce analgesia by affecting different pain pathways. We present two cases of neuropathic pain and two cases of nociceptive pain with a significant neuropathic component that were treated with transdermal buprenorphine. In each case, sufficient pain relief was obtained and no problems were encountered in switching from prior analgesic therapy with larger doses of other opioids.

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