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Gan To Kagaku Ryoho · Oct 2015
[Short-Term Outcome of TAS-102 for Refractory Metastatic Colorectal Cancer].
- Kazuhiko Yoshimatsu, Hajime Yokomizo, Mao Nakayama, Sachiyo Okayama, Masaya Satake, Akiko Sakuma, Yuki Yano, Atsuo Matsumoto, Takashi Fujimoto, Takebumi Usui, Kentaro Yamaguchi, Shunichi Shiozawa, Takeshi Shimakawa, Takao Katsube, and Yoshihiko Naritaka.
- Dept. of Surgery, Tokyo Women's Medical University Medical Center East.
- Gan To Kagaku Ryoho. 2015 Oct 1; 42 (10): 1316-8.
AbstractWe retrospectively analyzed 7 patients with refractory colorectal cancer treated with TAS-102 as salvage therapy. Subjects were 3 men and 4 women. The median age at initiation of TAS-102 was 71 years (range, 41-82 years). The number of target organs was 1 in 5 patients, 2 in 1 patient, and 3 in 1 patient. The median treatment courses were 2 courses (range, 1-6 courses). The reason for discontinuation was hematological toxicity in 1 patient, patients' wish in 3 patients, disease progression in 2 patients, and worsening of general condition in 1 patient. The median survival time since the first administration of TAS-102 was 9 months.
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