• Br J Surg · Mar 2020

    Multicenter Study Clinical Trial

    Carcinoembryonic antigen-specific, fluorescent image-guided cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for metastatic colorectal cancer.

    • D P Schaap, K S de Valk, M M Deken, R P J Meijer, J Burggraaf, A L Vahrmeijer, M Kusters, and SGM-101 study group.
    • Department of Surgery, Catharina Hospital, Eindhoven, Netherlands.
    • Br J Surg. 2020 Mar 1; 107 (4): 334-337.

    AbstractThis multicentre pilot study investigated the role of peroperative carcinoembryonic antigen (CEA)-specific fluorescence imaging during cytoreductive surgery-hyperthermic intraperitoneal chemotherapy surgery in peritoneal metastasized colorectal cancer. A correct change in peritoneal carcinomatosis index (PCI) owing to fluorescence imaging was seen in four of the 14 included patients. The use of SGM-101 in patients with peritoneally metastasized colorectal carcinoma is feasible, and allows intraoperative detection of tumour deposits and alteration of the PCI. Augmented reality guidance.© 2020 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd.

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