• Am J Emerg Med · Jun 2020

    Case Reports

    Oxidative storm in a patient with acute rotenone-containing plant poisoning.

    • Jiun-Hao Yu, Chun-Fa Huang, Te-Hao Wang, Dong-Zong Hung, Han-Wei Mu, and Chi-Syuan Pan.
    • Department of Emergency Medicine, China Medical University Hospital, Hsinchu, Taiwan. Electronic address: flykingyu@gmail.com.
    • Am J Emerg Med. 2020 Jun 1; 38 (6): 1296.e1-1296.e3.

    AbstractA 64-year-old woman presented with coma, seizure, and lactic acidosis after ingesting 80 yam bean seeds. This rotenone-containing seeds cause cellular asphyxia via blockage of the mitochondrial electron transport. Subsequent oxidative stress results in the formation of lipid peroxidation (LPO). Rotenone analysis via liquid chromatography mass spectrometry revealed the following: 31,590 ng/mL in cooked yam bean seed and 100 ng/mL in the blood. We attempted to use N-acetylcysteine to alleviate oxidative stress and documented the continuous decline in the plasma concentration of LPO.Copyright © 2020 Elsevier Inc. All rights reserved.

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