• Aust N Z J Obstet Gynaecol · Dec 2007

    Fetal growth restriction and other risk factors for stillbirth in a New Zealand setting.

    • Lesley M E McCowan, Maha George-Haddad, Tomasina Stacey, and John M D Thompson.
    • Department of Obstetrics and Gynaecology, University of Auckland, and National Women's Health, Auckland City Hospital, New Zealand. l.mccowan@auckland.ac.nz
    • Aust N Z J Obstet Gynaecol. 2007 Dec 1; 47 (6): 450-6.

    BackgroundStillbirth affects almost 1% of pregnant women in the Western world but is still not a research priority.AimsTo assess in a cohort of stillbirths: the demographic risk factors, the prevalence of small for gestational age (SGA) by customised and population centiles, and the classification of death using the Perinatal Society of Australia and New Zealand Perinatal Death Classification (PSANZ-PDC).MethodsThe study population comprised 437 stillborn babies (born from 1993 to 2000 at National Women's Hospital, Auckland, New Zealand) and their mothers. The referent population for demographic factors was live births n=69 173.ResultsAfter multivariable analysis, risk factors for stillbirths were: Indian (odds ratio (OR) 1.85, 95%CI (1.18, 2.91)), or Pacific Islander (OR 1.65, 95%CI (1.27, 2.14)); smoking (OR 1.33, 95%CI (0.99, 1.79)) or unknown smoking status (OR 2.87, 95%CI (2.30, 3.58)); nulliparity (OR 1.42, 95%CI (1.10, 1.83)), and para 2 (OR 1.36, 95%CI (1.01, 1.83)). One hundred and twenty-nine (46%) stillbirths born>or=24 weeks (n=278) were SGA by customised, and 94 (34%) by population centiles. Customised SGA was more common in preterm versus term stillbirths (101 of 198 (51%) vs 28 of 80 (35%), respectively, P=0.02) but rates of population SGA did not differ (72 of 198 (36%) vs 22 of 80 (28%) P=0.16). 'Spontaneous preterm' was the most common cause of stillbirth at <28 weeks and 'unexplained' at >or=28 weeks using PSANZ-PDC classification.ConclusionsThis study again emphasises the importance of suboptimal fetal growth as an important risk factor for stillbirth. Customised centiles identified more stillborn babies as SGA than population centiles especially preterm.

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