• Katsuya Hirata, Masahiro Nishihara, Yukari Oshima, Shinya Hirano, and Hiroyuki Kitajima.
• Department of Neonatal Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
• Am J Perinatol. 2014 May 1; 31 (5): 435-40.

ObjectiveThe aim of this article is to evaluate the accuracy, precision, and safety of transcutaneous carbon dioxide tension (TcPCO2) monitoring at different electrode temperatures in preterm infants in the early postnatal period.Study DesignA total of 26 neonates with a median birth weight of 974 g (432-1,694 g) and gestational age of 28.0 weeks (26.1-31.3 weeks) were studied in the first 5 days of life. A total of 252 simultaneous pairs (TcPCO2 and arterial carbon dioxide tension [PaCO2]) were analyzed at 38, 39, and 40°C at 26 and 27 weeks, and at 38, 39, 40, and 42°C at 28 to 31 weeks.ResultsThe mean difference of TcPCO2 and PaCO2 (bias) increased from 3.93 mm Hg at 42°C to 5.64 mm Hg at 40°C, 6.58 mm Hg at 39°C, and 6.07 mm Hg at 38°C. Standard deviation (SD) of the bias increased from 4.17 mm Hg at 42°C to 4.76 mm Hg at 40°C, 5.29 mm Hg at 39°C, and 5.07 mm Hg at 38°C. Adverse skin lesions were not observed.ConclusionTcPCO2 measurements are the most accurate and precise at an electrode temperature of 42°C. However, in premature babies, monitoring at 38, 39, and 40°C is possible provided a bias correction of 6 mm Hg and SD of 5 mm Hg are applied.Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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