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Journal of critical care · Jun 2020
One-year survival in patients with solid tumours discharged alive from the intensive care unit after unplanned admission: A retrospective study.
- Edith Borcoman, Axelle Dupont, Eric Mariotte, Ludovic Doucet, Adrien Joseph, Akli Chermak, Sandrine Valade, Matthieu Resche-Rigon, Elie Azoulay, and Virginie Lemiale.
- Medical ICU, APHP Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France.
- J Crit Care. 2020 Jun 1; 57: 36-41.
PurposeOutcomes in cancer patients after unplanned ICU admission was reassessed.Methodsretrospective cohort of patients with solid tumours admitted to ICU over a 10 years period.Results622 patients (age 62 [53-70]) were analysed. The most common primary sites of cancer were lung (n = 133; 21.4%) and digestive tract (n = 126; 20.2%) The ICU mortality rate was 22.2% (n = 138). Among 470 ICU survivors, the 1-year mortality was 41.3% (95% CI, 36-45.9) (n = 167). Factors independently associated with 1-year mortality were ICU admission after 2010 (HR 0.53 (0.37-0.76), p < .001), disease status (respectively, HR = 1.88 (1.0.2-3.45), p = .002) for locally advanced cancer and HR = 2.23 (1.35-3.67), p = .003) for metastatic cancer), poor performance status (HR = 1.58 (1.08-2.31), p = .019), newly diagnosed cancer at ICU admission (HR = 2.02 (1.28-3.20), p = .003), inability to receive oncologic treatment after ICU discharge (HR = 5.34 (3.49-8.18), p < .001) and decision to withhold life-sustaining treatment during ICU stay (HR = 2.34 (1.50-3.65), p < .001).ConclusionsAmong the factors associated with one-year mortality after ICU discharge, the possibility of receiving oncologic treatment after ICU discharge seems crucial.Copyright © 2020. Published by Elsevier Inc.
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