• Robert Ryu, Angelique Do, Julie Chan, Jason Cuellar, Wouter Schievink, and Eli M Baron.
• Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, California, USA.
• World Neurosurg. 2020 May 1; 137: 119-125.

BackgroundLumbar total disc replacement is increasingly becoming a more common treatment for discogenic low back pain refractory to conservative measures. Nevertheless, several complications have been reported, including, among others, wound infection, vascular injury, retrograde ejaculation, postsympathectomy syndrome, ileus, and cerebrospinal fluid (CSF) leak. Although CSF leakage is rare, we discuss a case of CSF leakage and the diagnosis and management of CSF leakage after lumbar total disc replacement.Case DescriptionA 25-year-old man had presented with discogenic low back pain caused by degenerative disc disease of 9 years' duration. His symptoms were exacerbated by activity, worse with sitting, and relieved by ice baths. He developed a cerebrospinal fluid leak after L5-S1 lumbar total disc replacement.ConclusionsOur patient ultimately required device removal, direct repair, and replacement with a different prosthesis to treat his CSF leak.Copyright © 2020 Elsevier Inc. All rights reserved.

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