• Acta Anaesthesiol Scand · Apr 1994

    Randomized Controlled Trial Comparative Study Clinical Trial

    Dixyrazine premedication for cataract surgery. A comparison with diazepam.

    • M Oikkonen, H Heine, U Salminen, O Romppanen, and P Inberg.
    • Department of Anaesthesia, Tampere University Hospital, Finland.
    • Acta Anaesthesiol Scand. 1994 Apr 1; 38 (3): 214-7.

    AbstractPeroral dixyrazine (15-30 mg, n = 50) and diazepam (4-10 mg, n = 50) were used as premedicants for geriatric patients having cataract surgery under regional block. Compared to the diazepam patients, a larger number of the dixyrazine medicated patients appeared anxious, and there was a statistically significant difference between the groups, when summing up changes in anxiety throughout the study period. The dixyrazine patients needed more frequent supplementation with intravenous sedative drugs, compared with their diazepam counterparts. Peroral dixyrazine is an applicable choice for calm patients, when only slight sedation, or avoidance of somnolence are required.

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