• David Vandroux, Hugo Kerambrun, Cyril Ferdynus, Nicolas Allou, Jérôme Allyn, Bernard-Alex Gaüzère, Olivier Martinet, and Julien Jabot.
• Cardiothoracic Intensive Care Unit, Dupuytren II Hospital, University Teaching Hospital of Limoges, Limoges, France; René Labusquière Centre of Tropical Medicine, University of Bordeaux, Bordeaux, France; UMR 1094 Neuroépidémiologie Tropicale, University of Limoges, Limoges, France. Electronic address: vandroux.david@gmail.com.
• J. Cardiothorac. Vasc. Anesth. 2020 Jun 1; 34 (6): 1426-1430.

ObjectivesThe aim of the present study was to assess the post-pandemic mortality of influenza in patients receiving venovenous extracorporeal membrane oxygenation (VV-ECMO) in Reunion Island, France, by comparing the incidence with other patients undergoing VV-ECMO.DesignRetrospective, descriptive, and single-center cohort study. The primary outcome was the standardized mortality ratio for influenza based on the quartiles of the Respiratory Extracorporeal Membrane Oxygenation Survival Prediction score (RESP Score) in the reference population of patients undergoing VV-ECMO.SettingIntensive care unit (ICU), Felix Guyon Hospital, University Teaching Hospital of La Réunion, La Réunion, France.ParticipantsConsecutive patients on ECMO with positive polymerase chain reaction for influenza.InterventionsNone.Measurements And Main ResultsOne hundred twenty-seven consecutive patients were hospitalized in the ICU with a positive influenza polymerase chain reaction from January 2013 to December 2017. Twenty-four influenza patients underwent ECMO including 18 patients with VV-ECMO. During this period, 72 patients requiring VV-ECMO were hospitalized in the ICU. The overall mortality rate of influenza patients on VV-ECMO was 61% versus 46% for non-influenza patients. The standardized mortality ratio per quartile of RESP Score was 1.28 (95% confidence interval 0.61-2.35).ConclusionsIn Reunion, the mortality of patients undergoing VV-ECMO for severe influenza is not lower than the expected mortality of all patients undergoing VV-ECMO.Copyright © 2020 Elsevier Inc. All rights reserved.

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