• Sanjay R Patel, Jia Weng, Michael Rueschman, Katherine A Dudley, Jose S Loredo, Yasmin Mossavar-Rahmani, Maricelle Ramirez, Alberto R Ramos, Kathryn Reid, Ashley N Seiger, Daniela Sotres-Alvarez, Phyllis C Zee, and Rui Wang.
• Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
• Sleep. 2015 Sep 1; 38 (9): 1497-503.

Study ObjectivesWhile actigraphy is considered objective, the process of setting rest intervals to calculate sleep variables is subjective. We sought to evaluate the reproducibility of actigraphy-derived measures of sleep using a standardized algorithm for setting rest intervals.DesignObservational study.SettingCommunity-based.ParticipantsA random sample of 50 adults aged 18-64 years free of severe sleep apnea participating in the Sueño sleep ancillary study to the Hispanic Community Health Study/Study of Latinos.InterventionsN/A.Measurements And ResultsParticipants underwent 7 days of continuous wrist actigraphy and completed daily sleep diaries. Studies were scored twice by each of two scorers. Rest intervals were set using a standardized hierarchical approach based on event marker, diary, light, and activity data. Sleep/wake status was then determined for each 30-sec epoch using a validated algorithm, and this was used to generate 11 variables: mean nightly sleep duration, nap duration, 24-h sleep duration, sleep latency, sleep maintenance efficiency, sleep fragmentation index, sleep onset time, sleep offset time, sleep midpoint time, standard deviation of sleep duration, and standard deviation of sleep midpoint. Intra-scorer intraclass correlation coefficients (ICCs) were high, ranging from 0.911 to 0.995 across all 11 variables. Similarly, inter-scorer ICCs were high, also ranging from 0.911 to 0.995, and mean inter-scorer differences were small. Bland-Altman plots did not reveal any systematic disagreement in scoring.ConclusionsWith use of a standardized algorithm to set rest intervals, scoring of actigraphy for the purpose of generating a wide array of sleep variables is highly reproducible.© 2015 Associated Professional Sleep Societies, LLC.

21 keywords...

hide…