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- D A Mickle and R D Weisel.
- Department of Clinical Biochemistry, Toronto Hospital, Ontario.
- Can J Cardiol. 1993 Jan 1; 9 (1): 89-93.
AbstractOxidant injury contributes to myocardial stunning, and cardiac ischemic and reperfusion injury. Vitamin E is the major--and perhaps the only--lipid soluble, chain-breaking antioxidant in the heart. Vitamin E and its analogues potentially offer significant advantages for the prevention of ischemic and reperfusion injury. Recent investigations have suggested that modified vitamin E analogues may be more efficacious than vitamin E and may permit myocardial salvage from acute myocardial ischemic injury.
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