• Nihon Kyobu Shikkan Gakkai Zasshi · Mar 1992

    [Immunohistochemical analysis of CA19-9, SLX, and CA125 in adenoid cystic carcinoma of trachea and bronchus].

    • S Tamura, K Yamaguchi, M Terada, T Nakano, J Maeda, N Iwahashi, T Hada, and K Higashino.
    • Third Department of Internal Medicine, Hyogo College of Medicine, Japan.
    • Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Mar 1; 30 (3): 407-11.

    AbstractWe examined the usefulness of 3 carbohydrate antigens, CA19-9, CA125, and SLX, as tumor markers in adenoid cystic carcinoma of the trachea and bronchus, immunohistochemically and clinically. CA19-9 and SLX were detected immunohistochemically in normal tracheal and bronchial glands, but CA125 was not detected. Bronchial secretions obtained from 7 patients without cancer contained high levels of these 3 carbohydrate antigens. There was positive immunohistochemical staining for CA19-9, CA125, and SLX in 5 of 9, 1 of 9, and 3 of 8 patients with tracheal or bronchial adenoid cystic carcinoma, respectively. In a case of bronchial adenoid cystic carcinoma in whom pretreatment serum CA19-9 showed a very high level, this marker changed in parallel with the clinical course. These results suggest the possibility that CA19-9 and SLX could be used as useful markers in patients with tracheal and bronchial adenoid cystic carcinoma.

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