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- Tero Ahola, Therese Couderc, Therese Courderc, Lisa F P Ng, David Hallengärd, Ann Powers, Marc Lecuit, Mariano Esteban, Andres Merits, Pierre Roques, and Peter Liljeström.
- 1 Department of Food and Environmental Sciences, University of Helsinki , Helsinki, Finland .
- Vector Borne Zoonotic Dis. 2015 Apr 1; 15 (4): 250-7.
AbstractCurrently, there are no licensed vaccines or therapies available against chikungunya virus (CHIKV), and these were subjects discussed during a CHIKV meeting recently organized in Langkawi, Malaysia. In this review, we chart the approaches taken in both areas. Because of a sharp increase in new data in these fields, the present paper is complementary to previous reviews by Weaver et al. in 2012 and Kaur and Chu in 2013 . The most promising antivirals so far discovered are reviewed, with a special focus on the virus-encoded replication proteins as potential targets. Within the vaccines in development, our review emphasizes the various strategies in parallel development that are unique in the vaccine field against a single disease.
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