• Neuroimaging Clin. N. Am. · Aug 2019

    Review

    MR Imaging of Normal Brain Development.

    • Matthew J Barkovich and Anthony James Barkovich.
    • Neuroradiology Section, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, Room S257, San Francisco, CA 94143-0628, USA.
    • Neuroimaging Clin. N. Am. 2019 Aug 1; 29 (3): 325-337.

    AbstractNormal brain development is best evaluated by MR imaging in the fetal and pediatric patient. As the developing brain grows, myelinates, and sulcates rapidly, understanding the normal appearance of the brain throughout development is critical. The fetal brain can be evaluated by MR imaging after 16 weeks gestational age, both morphologically and biometrically. Sulcation of the fetal brain lags behind premature neonates of equivalent gestational age. Sensory axons generally myelinate before motor axons with central to peripheral and dorsal to ventral myelination gradients. By 2 years of age, the brain has a near adult appearance by conventional anatomic MR imaging.Copyright © 2019 Elsevier Inc. All rights reserved.

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