• Neuroimaging Clin. N. Am. · Aug 2019

    Review

    Diffusion Tensor Imaging of Brain Malformations: Exploring the Internal Architecture.

    • Avner Meoded and Huisman Thierry A G M TAGM Edward B. Singleton Department of Radiology, Texas Children's Hospital, 6701 Fannin Street, Suite 470, Houston, TX 77030, USA..
    • Johns Hopkins All Children's Hospital, 501 6th Avenue South, St Petersburg, FL 33701, USA. Electronic address: ameoded1@jhmi.edu.
    • Neuroimaging Clin. N. Am. 2019 Aug 1; 29 (3): 423-434.

    AbstractDiffusion tensor imaging (DTI) is an advanced MR imaging technique that provides noninvasive qualitative and quantitative information about the white matter microarchitecture. By measuring the three-dimensional directional characteristics of water molecule diffusion/mobility, DTI generates unique tissue contrasts that are used to study the axonal organization of the central nervous system. Its applications include quantitative evaluation of the brain connectivity, development, and white matter diseases. This article reviews DTI and fiber tractography findings in several brain malformations and highlights the added value of DTI and fiber tractography compared with conventional MR imaging.Copyright © 2019 Elsevier Inc. All rights reserved.

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