• La Revue du praticien · Feb 2002

    Review

    [Biotherapy of neuroendocrine tumors].

    • Philippe Chanson and Michel Ducreux.
    • Service d'endocrinologie et des maladies de la reproduction Centre hospitalier universitaire de Bicêtre 94275 Le Kremlin-Bicêtre. pchanson@club-internet.fr
    • Rev Prat. 2002 Feb 1; 52 (3): 280-4.

    AbstractThe somatostatin analogues have an excellent symptomatic therapeutic effect (60-90% responses in carcinoid syndrome) which permits an amelioration in the quality of life, particularly in patients with metastatic tumours. The availability of long-acting somatostatin analogues assuring stable plasma concentrations over several weeks (thanks to progressive liberation) further facilitates the use of these medications by allowing a reduction in the number of injections. Interferon also has an anti-secretory effect, albeit inferior to that of the somatostatin analogues, but potentially of interest in the case of resistance to these products.

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