• Leonel Lagunes, Belen Encina, and Sergio Ramirez-Estrada.
• Critical Care Department, Hospital Especialidades Médicas de la Salud, San Luis Potosi, Mexico;; Medicine Department, Universitat Autónoma de Barcelona (UAB), Barcelona, Spain.
• Ann Transl Med. 2016 Sep 1; 4 (17): 330.

AbstractSepsis and septic shock is one of the leading causes of death worldwide. Antibiotics, fluid resuscitation support of vital organ function and source control are the cornerstones for the treatment of these patients. Source control measures include all those actions taken in the process of care to control the foci of infection and to restore optimal function of the site of infection. Source control represents the multidisciplinary team required in order to optimize critical care for septic shock patients. In the last decade an increase interest on fluids, vasopressors, antibiotics, and organ support techniques in all aspects whether time, dose and type of any of those have been described. However information of source control measures involving minimal invasion and new techniques, time of action and outcome without it, is scarce. In this review the authors resumes new information, recommendations and future directions on this matter when facing the more common types of infections.

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